Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/PYGM/?format=api
{ "data": { "type": "Gene", "id": "PYGM", "attributes": { "go_molecular_function": [ "pyridoxal phosphate binding", "transferase activity", "glycosyltransferase activity", "nucleotide binding", "glycogen phosphorylase activity", "linear malto-oligosaccharide phosphorylase activity", "catalytic activity", "1,4-alpha-oligoglucan phosphorylase activity", "SHG alpha-glucan phosphorylase activity" ], "pathway_id": [ "R-HSA-71387", "kegg_path:hsa04922", "R-HSA-1430728", "kegg_path:hsa01100", "kegg_path:hsa04910", "R-HSA-70221", "kegg_path:hsa00500", "R-HSA-8982491", "kegg_path:hsa04217", "kegg_path:hsa04931" ], "essential_gene": null, "status": null, "uniprot_acc": "P11217", "ensembl_id": "ENSG00000068976", "entrez_id": "5837", "chromosome_number": "11" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "982" }, { "type": "SmallVariant", "id": "1773" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PYGM/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PYGM/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "315" }, { "type": "GeneCombination", "id": "586" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PYGM/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PYGM/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PYGM/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.939692", "status": "CU", "curator": null, "submitter": "cnachteg" } }