Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/PLXNA1/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "785", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 2.854e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 3.681e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 9.823e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.305097, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126736704, "genomic_position_hg38": 127017861, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.201206", "ref_allele": "C", "alt_allele": "T", "cdna_change": null, "protein_change": "p.Ala1210Val", "transcript_id": null, "dbsnp_id": "rs758654359", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI358" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/785/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/785/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/785/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/785/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/785/?format=api" } }, { "type": "SmallVariant", "id": "1409", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.183e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0008789, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 6.784e-05, "gnomad_NFE_maf": 6.567e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001176 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.844216, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126733121, "genomic_position_hg38": 127014278, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.949686", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2507G>A", "protein_change": "p.Arg836His", "transcript_id": "NM_032242.3", "dbsnp_id": "rs374673201", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI648" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1409/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1409/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1409/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1409/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1409/?format=api" } }, { "type": "SmallVariant", "id": "1410", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 9.373e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.059e-05, "gnomad_OTH_maf": 0.0001841, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.455952, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126723517, "genomic_position_hg38": 127004674, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.956413", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1582C>T", "protein_change": "p.Arg528Trp", "transcript_id": "NM_032242.3", "dbsnp_id": "rs769333083", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI648" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1410/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1410/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1410/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1410/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1410/?format=api" } }, { "type": "SmallVariant", "id": "1411", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.540335, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126741651, "genomic_position_hg38": 127022808, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.963247", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.4352A>G", "protein_change": "p.Lys1451Arg", "transcript_id": "NM_032242.3", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI649" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1411/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1411/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1411/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1411/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1411/?format=api" } }, { "type": "SmallVariant", "id": "1412", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.958e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 6.533e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.31948, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126708295, "genomic_position_hg38": 126989452, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.970006", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.859G>A", "protein_change": "p.Val287Met", "transcript_id": "NM_032242.3", "dbsnp_id": "rs749748554", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI649" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1412/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1412/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1412/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1412/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1412/?format=api" } }, { "type": "SmallVariant", "id": "1414", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.995225, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126723541, "genomic_position_hg38": 127004698, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.983480", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1606G>A", "protein_change": "p.Val536Ile", "transcript_id": "NM_032242.3", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI650" }, { "type": "Combination", "id": "OLI651" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1414/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1414/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1414/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1414/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1414/?format=api" } }, { "type": "SmallVariant", "id": "1418", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.228615, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126751634, "genomic_position_hg38": 127032791, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.010507", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.5550C>A", "protein_change": "p.Ser1850Arg", "transcript_id": "NM_032242.3", "dbsnp_id": "rs1259524882", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI652" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1418/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1418/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1418/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1418/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1418/?format=api" } }, { "type": "SmallVariant", "id": "1421", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.973e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.892e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 3.268e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.611792, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126708391, "genomic_position_hg38": 126989548, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.030654", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.955C>T", "protein_change": "p.Arg319Trp", "transcript_id": "NM_032242.3", "dbsnp_id": "rs374901417", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI653" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1421/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1421/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1421/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1421/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1421/?format=api" } }, { "type": "SmallVariant", "id": "1423", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.812535, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126722249, "genomic_position_hg38": 127003406, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.044145", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.1454C>T", "protein_change": "p.Pro485Leu", "transcript_id": "NM_032242.3", "dbsnp_id": "rs2079050302", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI654" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1423/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1423/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1423/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1423/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1423/?format=api" } }, { "type": "SmallVariant", "id": "1910", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.645003, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 126722280, "genomic_position_hg38": 127003437, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:52.061745", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.1485C>A", "protein_change": "p.Asn495Lys", "transcript_id": "NM_032242.3", "dbsnp_id": "rs2079050702", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI874" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1910/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1910/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1910/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1910/gene/?format=api" }, "data": { "type": "Gene", "id": "PLXNA1" } } }, 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