Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/PIK3CD/?format=api
{ "data": { "type": "Gene", "id": "PIK3CD", "attributes": { "go_molecular_function": [ "['phosphatidylinositol kinase activity', 'phosphatidylinositol 3-kinase activity', '1-phosphatidylinositol-3-kinase activity', 'phosphatidylinositol-3,4-bisphosphate 5-kinase activity', 'protein binding', '1-phosphatidylinositol-4-phosphate 3-kinase activity', 'phosphatidylinositol-4,5-bisphosphate 3-kinase activity', 'kinase activity', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa00562", "kegg_path:hsa01100", "kegg_path:hsa01521", "kegg_path:hsa01522", "kegg_path:hsa01524", "kegg_path:hsa04012", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04024", "kegg_path:hsa04062", "kegg_path:hsa04066", "kegg_path:hsa04068", "kegg_path:hsa04070", "kegg_path:hsa04071", "kegg_path:hsa04072", "kegg_path:hsa04140", "kegg_path:hsa04150", "kegg_path:hsa04151", "kegg_path:hsa04152", "kegg_path:hsa04210", "kegg_path:hsa04211", "kegg_path:hsa04213", "kegg_path:hsa04218", "kegg_path:hsa04360", "kegg_path:hsa04370", "kegg_path:hsa04380", "kegg_path:hsa04510", "kegg_path:hsa04550", "kegg_path:hsa04611", "kegg_path:hsa04613", "kegg_path:hsa04620", "kegg_path:hsa04625", "kegg_path:hsa04630", "kegg_path:hsa04650", "kegg_path:hsa04660", "kegg_path:hsa04662", "kegg_path:hsa04664", "kegg_path:hsa04666", "kegg_path:hsa04668", "kegg_path:hsa04670", "kegg_path:hsa04722", "kegg_path:hsa04725", "kegg_path:hsa04750", "kegg_path:hsa04810", "kegg_path:hsa04910", "kegg_path:hsa04914", "kegg_path:hsa04915", "kegg_path:hsa04917", "kegg_path:hsa04919", "kegg_path:hsa04923", "kegg_path:hsa04926", "kegg_path:hsa04929", "kegg_path:hsa04930", "kegg_path:hsa04931", "kegg_path:hsa04932", "kegg_path:hsa04933", "kegg_path:hsa04935", "kegg_path:hsa04960", "kegg_path:hsa04973", "kegg_path:hsa05010", "kegg_path:hsa05017", "kegg_path:hsa05020", "kegg_path:hsa05100", "kegg_path:hsa05131", "kegg_path:hsa05132", "kegg_path:hsa05135", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05160", "kegg_path:hsa05161", "kegg_path:hsa05162", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05166", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05169", "kegg_path:hsa05170", "kegg_path:hsa05171", "kegg_path:hsa05200", "kegg_path:hsa05203", "kegg_path:hsa05205", "kegg_path:hsa05206", "kegg_path:hsa05210", "kegg_path:hsa05211", "kegg_path:hsa05212", "kegg_path:hsa05213", "kegg_path:hsa05214", "kegg_path:hsa05215", "kegg_path:hsa05218", "kegg_path:hsa05220", "kegg_path:hsa05221", "kegg_path:hsa05222", "kegg_path:hsa05223", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "kegg_path:hsa05230", "kegg_path:hsa05231", "kegg_path:hsa05235", "kegg_path:hsa05418", "kegg_path:hsa00562", "kegg_path:hsa01100", "kegg_path:hsa01521", "kegg_path:hsa01522", "kegg_path:hsa01524", "kegg_path:hsa04012", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04024", "kegg_path:hsa04062", "kegg_path:hsa04066", "kegg_path:hsa04068", "kegg_path:hsa04070", "kegg_path:hsa04071", "kegg_path:hsa04072", "kegg_path:hsa04140", "kegg_path:hsa04150", "kegg_path:hsa04151", "kegg_path:hsa04152", "kegg_path:hsa04210", "kegg_path:hsa04211", "kegg_path:hsa04213", "kegg_path:hsa04218", "kegg_path:hsa04360", "kegg_path:hsa04370", "kegg_path:hsa04380", "kegg_path:hsa04510", "kegg_path:hsa04550", "kegg_path:hsa04611", "kegg_path:hsa04613", "kegg_path:hsa04620", "kegg_path:hsa04625", "kegg_path:hsa04630", "kegg_path:hsa04650", "kegg_path:hsa04660", "kegg_path:hsa04662", "kegg_path:hsa04664", "kegg_path:hsa04666", "kegg_path:hsa04668", "kegg_path:hsa04670", "kegg_path:hsa04722", "kegg_path:hsa04725", "kegg_path:hsa04750", "kegg_path:hsa04810", "kegg_path:hsa04910", "kegg_path:hsa04914", "kegg_path:hsa04915", "kegg_path:hsa04917", "kegg_path:hsa04919", "kegg_path:hsa04923", "kegg_path:hsa04926", "kegg_path:hsa04929", "kegg_path:hsa04930", "kegg_path:hsa04931", "kegg_path:hsa04932", "kegg_path:hsa04933", "kegg_path:hsa04935", "kegg_path:hsa04960", "kegg_path:hsa04973", "kegg_path:hsa05010", "kegg_path:hsa05017", "kegg_path:hsa05020", "kegg_path:hsa05100", "kegg_path:hsa05131", "kegg_path:hsa05132", "kegg_path:hsa05135", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05160", "kegg_path:hsa05161", "kegg_path:hsa05162", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05166", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05169", "kegg_path:hsa05170", "kegg_path:hsa05171", "kegg_path:hsa05200", "kegg_path:hsa05203", "kegg_path:hsa05205", "kegg_path:hsa05206", "kegg_path:hsa05210", "kegg_path:hsa05211", "kegg_path:hsa05212", "kegg_path:hsa05213", "kegg_path:hsa05214", "kegg_path:hsa05215", "kegg_path:hsa05218", "kegg_path:hsa05220", "kegg_path:hsa05221", "kegg_path:hsa05222", "kegg_path:hsa05223", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "kegg_path:hsa05230", "kegg_path:hsa05231", "kegg_path:hsa05235", "kegg_path:hsa05418", "R-HSA-1257604", "R-HSA-1266738", "R-HSA-1280215", "R-HSA-1280218", "R-HSA-1430728", "R-HSA-1483255", "R-HSA-1483257", "R-HSA-162582", "R-HSA-1643685", "R-HSA-1660499", "R-HSA-168256", "R-HSA-199418", "R-HSA-2219528", "R-HSA-2219530", "R-HSA-422475", "R-HSA-449147", "R-HSA-451927", "R-HSA-512988", "R-HSA-556833", "R-HSA-5663202", "R-HSA-6811558", "R-HSA-8853659", "R-HSA-9006335", "R-HSA-9006925", "R-HSA-9027276", "R-HSA-912526", "R-HSA-912631", "R-HSA-9675108", "R-HSA-983695", "R-HSA-983705" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "O00329", "ensembl_id": "None", "entrez_id": "ENSG00000171608", "chromosome_number": "1" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3634" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3CD/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIK3CD/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1222" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3CD/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIK3CD/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3CD/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2024-02-29T15:02:20.783940", "status": "CU", "curator": null, "submitter": "cnachteg" } }