Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/NRP2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "623", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Axon guidance", "Nervous system development", "Signal Transduction", "Developmental Biology" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.275557" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI856" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/623/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/623/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "NRP2" }, { "type": "Gene", "id": "SEMA4D" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/623/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/623/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/623/?format=api" } }, { "type": "GeneCombination", "id": "636", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:20.165832" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI869" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/636/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/636/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "NRP2" }, { "type": "Gene", "id": "PLXNB1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/636/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/636/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/636/?format=api" } }, { "type": "GeneCombination", "id": "644", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Axon guidance", "Nervous system development", "Signal Transduction", "Developmental Biology" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:20.772447" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI878" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/644/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/644/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "NRP2" }, { "type": "Gene", "id": "PLXNB1" }, { "type": "Gene", "id": "RELN" }, { "type": "Gene", "id": "TLE4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/644/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/644/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/644/?format=api" } }, { "type": "GeneCombination", "id": "658", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:21.470406" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI893" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/658/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/658/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "LHB" }, { "type": "Gene", "id": "NRP2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/658/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/658/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/658/?format=api" } }, { "type": "GeneCombination", "id": "664", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Nervous system development", "L1CAM interactions", "Axon guidance", "Human papillomavirus infection", "Signaling by Receptor Tyrosine Kinases", "Developmental Biology", "PI3K-Akt signaling pathway", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:21.757037" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI901" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/664/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/664/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "EGFR" }, { "type": "Gene", "id": "NRP2" }, { "type": "Gene", "id": "RELN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/664/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/664/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/664/?format=api" } }, { "type": "GeneCombination", "id": "926", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.947493" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1321" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/926/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/926/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "NRP2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/926/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/926/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/926/?format=api" } } ] }