Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/MYO7A/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "509", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": null, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "11", "annotation_flag": "not_found_in_databases", "lastmodified": "2021-10-28T16:03:11.845165", "ref_allele": "None", "alt_allele": "None", "cdna_change": "None", "protein_change": "p.Lys542GlnfsTer5", "transcript_id": "None", "dbsnp_id": "NA", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI262" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/509/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/509/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/509/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/509/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/509/?format=api" } }, { "type": "SmallVariant", "id": "206", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 5.275594, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76901894, "genomic_position_hg38": 77190849, "chromosome": "11", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:41.732425", "ref_allele": "CT", "alt_allele": "C", "cdna_change": "c.3904delT", "protein_change": "p.Tyr1302fsTer97", "transcript_id": "NM_000260.4", "dbsnp_id": "NA", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI101" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/206/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/206/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/206/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/206/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/206/?format=api" } }, { "type": "SmallVariant", "id": "207", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.205e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 5.565e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.773e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.075012, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76873900, "genomic_position_hg38": 77162854, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.738297", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Gly519Asp", "transcript_id": null, "dbsnp_id": "rs111033206", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI100" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/207/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/207/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/207/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/207/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/207/?format=api" } }, { "type": "SmallVariant", "id": "211", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 4.877256, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76890090, "genomic_position_hg38": 77179044, "chromosome": "11", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:41.762440", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.2283-1G>T", "protein_change": null, "transcript_id": "NM_000260.3", "dbsnp_id": "rs397516295", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI102" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/211/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/211/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/211/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/211/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/211/?format=api" } }, { "type": "SmallVariant", "id": "213", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.754166, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76925023, "genomic_position_hg38": 77213978, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.774330", "ref_allele": "T", "alt_allele": "C", "cdna_change": null, "protein_change": "p.Leu2186Pro", "transcript_id": null, "dbsnp_id": "rs876657417", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI103" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/213/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/213/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/213/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/213/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/213/?format=api" } }, { "type": "SmallVariant", "id": "218", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.924e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 3.759e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 7.816e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001356, "gnomad_OTH_maf": 0.0002128, "gnomad_SAS_maf": 4.193e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.652316, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76901093, "genomic_position_hg38": 77190048, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.804814", "ref_allele": "C", "alt_allele": "T", "cdna_change": null, "protein_change": "p.Pro1220Leu", "transcript_id": null, "dbsnp_id": "rs727504710", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI105" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/218/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/218/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/218/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/218/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/218/?format=api" } }, { "type": "SmallVariant", "id": "221", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0009486, "gnomad_AFR_maf": 0.0001338, "gnomad_AMR_maf": 0.0006144, "gnomad_ASJ_maf": 0.0006012, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0001404, "gnomad_NFE_maf": 0.001769, "gnomad_OTH_maf": 0.0006682, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.000512, "ESP_EA_maf": 0.001569 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.882964, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 76868392, "genomic_position_hg38": 77157346, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.823176", "ref_allele": "A", "alt_allele": "G", "cdna_change": null, "protein_change": "p.Lys268Arg", "transcript_id": null, "dbsnp_id": "rs184866544", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI106" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/221/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/221/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/221/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/221/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/221/?format=api" } }, { "type": "SmallVariant", "id": "503", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.063149, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76890119, "genomic_position_hg38": 77179073, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.495692", "ref_allele": "G", "alt_allele": "T", "cdna_change": null, "protein_change": "p.Ala771Ser", "transcript_id": null, "dbsnp_id": "rs782384464", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI259" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/503/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/503/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/503/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/503/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/503/?format=api" } }, { "type": "SmallVariant", "id": "507", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.871259, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 76885940, "genomic_position_hg38": 77174894, "chromosome": "11", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.520950", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Val692Met", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI261" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/507/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/507/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/507/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/507/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/507/?format=api" } }, { "type": "SmallVariant", "id": "720", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0032, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0159, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.001502, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.909e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0203, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.956e-06, "gnomad_OTH_maf": 0.0005007, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 0.309211, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 76900350, "genomic_position_hg38": 77189305, "chromosome": "11", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:44.789571", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.3504-39T>C", "protein_change": null, "transcript_id": "NM_000260.3", "dbsnp_id": "rs192929996", "variant_effect": "unknown" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI343" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/720/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/720/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/720/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/720/gene/?format=api" }, "data": { "type": "Gene", "id": "MYO7A" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/720/?format=api" } }, { "type": "SmallVariant", "id": "727", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, 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