Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/ITGAV/?format=api
{ "data": { "type": "Gene", "id": "ITGAV", "attributes": { "go_molecular_function": [ "['transforming growth factor beta binding', 'C-X3-C chemokine binding', 'extracellular matrix binding', 'neuregulin binding', 'opsonin binding', 'extracellular matrix protein binding', 'fibronectin binding', 'protein kinase C binding', 'insulin-like growth factor I binding', 'fibroblast growth factor binding', 'protease binding', 'protein binding', 'metal ion binding', 'integrin binding', 'virus receptor activity', 'voltage-gated calcium channel activity', 'coreceptor activity']" ], "pathway_id": [ "kegg_path:hsa04145", "kegg_path:hsa04151", "kegg_path:hsa04510", "kegg_path:hsa04512", "kegg_path:hsa04514", "kegg_path:hsa04810", "kegg_path:hsa04919", "kegg_path:hsa05163", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05222", "kegg_path:hsa05410", "kegg_path:hsa05412", "kegg_path:hsa05414", "kegg_path:hsa05418", "kegg_path:hsa04145", "kegg_path:hsa04151", "kegg_path:hsa04510", "kegg_path:hsa04512", "kegg_path:hsa04514", "kegg_path:hsa04810", "kegg_path:hsa04919", "kegg_path:hsa05163", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05222", "kegg_path:hsa05410", "kegg_path:hsa05412", "kegg_path:hsa05414", "kegg_path:hsa05418", "R-HSA-109582", "R-HSA-1236973", "R-HSA-1236975", "R-HSA-1266738", "R-HSA-1280218", "R-HSA-1474244", "R-HSA-1566948", "R-HSA-162582", "R-HSA-168249", "R-HSA-168256", "R-HSA-194138", "R-HSA-202733", "R-HSA-210990", "R-HSA-2129379", "R-HSA-216083", "R-HSA-3000157", "R-HSA-3000170", "R-HSA-3000171", "R-HSA-3000178", "R-HSA-373760", "R-HSA-422475", "R-HSA-4420097", "R-HSA-445144", "R-HSA-6798695", "R-HSA-9006934", "R-HSA-9675108", "R-HSA-983169" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "P06756", "ensembl_id": "None", "entrez_id": "ENSG00000138448", "chromosome_number": "2" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2603" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITGAV/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITGAV/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "863" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITGAV/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITGAV/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ITGAV/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2023-05-16T12:02:32.353477", "status": "CU", "curator": null, "submitter": "cnachteg" } }