Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/IL17RD/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "770", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.463238, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 57199211, "genomic_position_hg38": 57165183, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.110627", "ref_allele": "C", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Gly35Val", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI354" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/770/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/770/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/770/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/770/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/770/?format=api" } }, { "type": "SmallVariant", "id": "776", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.002, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.0003535, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.003436, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 3.726e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0006635, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.180279, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57131719, "genomic_position_hg38": 57097691, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.149111", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Ser671Leu", "transcript_id": null, "dbsnp_id": "rs200787099", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI355" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/776/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/776/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/776/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/776/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/776/?format=api" } }, { "type": "SmallVariant", "id": "778", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.593e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 5.438e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 9.804e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.540381, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57139971, "genomic_position_hg38": 57105943, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.161882", "ref_allele": "C", "alt_allele": "T", "cdna_change": null, "protein_change": "p.Ala221Thr", "transcript_id": null, "dbsnp_id": "rs752263276", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI356" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/778/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/778/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/778/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/778/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/778/?format=api" } }, { "type": "SmallVariant", "id": "780", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 8.503e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0001148, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.471825, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57135384, "genomic_position_hg38": 57101356, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.174904", "ref_allele": "T", "alt_allele": "C", "cdna_change": null, "protein_change": "p.Ile329Met", "transcript_id": null, "dbsnp_id": "rs143634778", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI357" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/780/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/780/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/780/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/780/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/780/?format=api" } }, { "type": "SmallVariant", "id": "800", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 9.573e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.894e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0003237, "gnomad_NFE_maf": 0.0001326, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 3.271e-05, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.675698, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57135235, "genomic_position_hg38": 57101207, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.284183", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.1136A>G", "protein_change": "p.Tyr379Cys", "transcript_id": "NM_017563.4", "dbsnp_id": "rs369641068", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1594" }, { "type": "Combination", "id": "OLI365" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/800/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/800/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/800/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/800/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/800/?format=api" } }, { "type": "SmallVariant", "id": "802", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.583e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 9.93e-05, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 6.168e-05, "gnomad_OTH_maf": 0.0001631, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.725229, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57130437, "genomic_position_hg38": 57096409, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.297062", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2204C>T", "protein_change": "p.Ala735Val", "transcript_id": "NM_017563.4", "dbsnp_id": "rs587776979", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI366" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/802/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/802/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/802/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/802/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/802/?format=api" } }, { "type": "SmallVariant", "id": "1831", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0001602, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001472, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 9.757e-05, "gnomad_OTH_maf": 0.0001643, "gnomad_SAS_maf": 3.294e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.974089, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57140161, "genomic_position_hg38": 57106133, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.566981", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.572C>T", "protein_change": "p.Pro191Leu", "transcript_id": "NM_017563.4", "dbsnp_id": "rs200088377", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1344" }, { "type": "Combination", "id": "OLI837" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1831/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1831/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1831/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1831/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1831/?format=api" } }, { "type": "SmallVariant", "id": "1879", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.002, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 9.595e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001326, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.33181, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 57131630, "genomic_position_hg38": 57097602, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.865922", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.2101G>A", "protein_change": "p.Gly701Ser", "transcript_id": "NM_017563.4", "dbsnp_id": "rs533191655", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1108" }, { "type": "Combination", "id": "OLI858" }, { "type": "Combination", "id": "OLI908" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1879/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1879/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1879/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1879/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1879/?format=api" } }, { "type": "SmallVariant", "id": "1897", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 8.362e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001142, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.982678, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 57132139, "genomic_position_hg38": 57098111, "chromosome": "3", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.976526", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.1592G>T", "protein_change": "p.Arg531Met", "transcript_id": "NM_017563.4", "dbsnp_id": "rs564636157", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI868" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1897/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1897/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1897/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1897/gene/?format=api" }, "data": { "type": "Gene", "id": "IL17RD" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1897/?format=api" } }, { "type": "SmallVariant", "id": "2676", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0116, "KGP_genomes_AFR_maf": 0.0378, "KGP_genomes_AMR_maf": 0.0115, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.003001, "gnomad_AFR_maf": 0.03596, "gnomad_AMR_maf": 0.002132, "gnomad_ASJ_maf": 0.005133, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0002143, "gnomad_OTH_maf": 0.002435, "gnomad_SAS_maf": 3.621e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.406361, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 57131807, "genomic_position_hg38": 57097779, "chromosome": "3", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.568367", "ref_allele": "C", "alt_allele": "G", "cdna_change": "c.1924G>C", "protein_change": "p.Ala642Pro", "transcript_id": "NM_017563.5", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1268" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2676/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2676/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2676/relationships/gene_name?format=api", "related": 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