Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/HEXB/?format=api
{ "data": { "type": "Gene", "id": "HEXB", "attributes": { "go_molecular_function": [ "beta-N-acetylhexosaminidase activity", "N-acetyl-beta-D-galactosaminidase activity", "hydrolase activity, hydrolyzing O-glycosyl compounds", "hydrolase activity", "hydrolase activity, acting on glycosyl bonds", "identical protein binding" ], "pathway_id": [ "R-HSA-428157", "kegg_path:hsa00513", "R-HSA-1660662", "R-HSA-2022857", "R-HSA-71387", "R-HSA-1430728", "kegg_path:hsa00520", "kegg_path:hsa04142", "R-HSA-1630316", "kegg_path:hsa00531", "R-HSA-168256", "kegg_path:hsa00603", "R-HSA-5668914", "kegg_path:hsa00604", "R-HSA-2142845", "R-HSA-2160916", "R-HSA-168249", "kegg_path:hsa00511", "R-HSA-1643685", "R-HSA-3781865", "kegg_path:hsa00511", "R-HSA-556833", "R-HSA-6798695", "kegg_path:hsa00604", "kegg_path:hsa00603", "R-HSA-2024101", "kegg_path:hsa00531", "kegg_path:hsa04142", "kegg_path:hsa00520", "R-HSA-1638074", "R-HSA-1793185", "R-HSA-3656248", "kegg_path:hsa00513", "kegg_path:hsa01100", "kegg_path:hsa01100", "R-HSA-3560782" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "P07686", "ensembl_id": "ENSG00000049860", "entrez_id": "3074", "chromosome_number": "5" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "669" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HEXB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HEXB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "219" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HEXB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HEXB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HEXB/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.460255", "status": "CU", "curator": null, "submitter": "cnachteg" } }