Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/GRIN2C/?format=api
{ "data": { "type": "Gene", "id": "GRIN2C", "attributes": { "go_molecular_function": [ "['glutamate-gated calcium ion channel activity', 'ligand-gated ion channel activity', 'signaling receptor activity', 'transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential', 'NMDA glutamate receptor activity', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04020", "kegg_path:hsa04024", "kegg_path:hsa04080", "kegg_path:hsa04713", "kegg_path:hsa04720", "kegg_path:hsa04724", "kegg_path:hsa05010", "kegg_path:hsa05014", "kegg_path:hsa05017", "kegg_path:hsa05020", "kegg_path:hsa05022", "kegg_path:hsa05030", "kegg_path:hsa05031", "kegg_path:hsa05033", "kegg_path:hsa05034", "R-HSA-112314", "R-HSA-112315", "R-HSA-112316", "R-HSA-438064", "R-HSA-438066", "R-HSA-442755", "R-HSA-6794361", "R-HSA-6794362", "R-HSA-8849932", "R-HSA-9609736", "R-HSA-9617324", "R-HSA-9620244" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "Q14957", "ensembl_id": "None", "entrez_id": "ENSG00000161509", "chromosome_number": "17" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3086" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GRIN2C/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GRIN2C/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1035" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GRIN2C/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GRIN2C/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GRIN2C/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2023-05-16T12:02:33.324106", "status": "CU", "curator": null, "submitter": "cnachteg" } }