Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/GLI2/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "725", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.0003118, "gnomad_AFR_maf": 6.383e-05, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.002996, "gnomad_EAS_maf": 0.0003292, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001977, "gnomad_OTH_maf": 0.0001664, "gnomad_SAS_maf": 0.0005243, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 0.11627, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121726501, "genomic_position_hg38": 120968925, "chromosome": "2", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:44.821510", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.845+10G>A", "protein_change": null, "transcript_id": "NM_005270.5", "dbsnp_id": "rs199673018", "variant_effect": "unknown" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI344" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/725/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/725/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/725/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/725/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/725/?format=api" } }, { "type": "SmallVariant", "id": "735", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 0.381947, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121748101, "genomic_position_hg38": 120990525, "chromosome": "2", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:44.885631", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.4611C>T", "protein_change": "p.Leu1537=", "transcript_id": "NM_005270.4", "dbsnp_id": "rs1335405295", "variant_effect": "silent" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI347" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/735/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/735/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/735/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/735/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/735/?format=api" } }, { "type": "SmallVariant", "id": "1217", "attributes": { "frequencies": { "KGP_genomes_maf": 0.007, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0476, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.001, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.009701, "gnomad_AFR_maf": 0.0006164, "gnomad_AMR_maf": 0.0545, "gnomad_ASJ_maf": 9.932e-05, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.006376, "gnomad_NFE_maf": 0.00245, "gnomad_OTH_maf": 0.008975, "gnomad_SAS_maf": 0.002254, "ESP_AA_maf": 0.000227, "ESP_EA_maf": 0.001047 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.230653, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121747823, "genomic_position_hg38": 120990247, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:47.837235", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.4333C>T", "protein_change": "p.Leu1445Phe", "transcript_id": "NM_005270.4", "dbsnp_id": "rs146207623", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI575" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1217/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1217/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1217/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1217/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1217/?format=api" } }, { "type": "SmallVariant", "id": "1281", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0001075, "gnomad_AFR_maf": 6.527e-05, "gnomad_AMR_maf": 2.926e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0002205, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0005817 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.041912, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121747688, "genomic_position_hg38": 120990112, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.194830", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.4198G>T", "protein_change": "p.Gly1400Cys", "transcript_id": "NM_005270.4", "dbsnp_id": "rs143914758", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI599" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1281/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1281/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1281/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1281/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1281/?format=api" } }, { "type": "SmallVariant", "id": "2493", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0046, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0043, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0099, "KGP_genomes_SAS_maf": 0.0092, "gnomad_maf": 0.009353, "gnomad_AFR_maf": 0.002584, "gnomad_AMR_maf": 0.00318, "gnomad_ASJ_maf": 0.009724, "gnomad_EAS_maf": 5.437e-05, "gnomad_FIN_maf": 0.002494, "gnomad_NFE_maf": 0.01456, "gnomad_OTH_maf": 0.009612, "gnomad_SAS_maf": 0.01088, "ESP_AA_maf": 0.004085, "ESP_EA_maf": 0.01442 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.189697, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121748048, "genomic_position_hg38": 120990472, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.575598", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.4558G>A", "protein_change": "p.Asp1520Asn", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1159" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2493/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2493/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2493/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2493/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2493/?format=api" } }, { "type": "SmallVariant", "id": "2512", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.526353, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121712916, "genomic_position_hg38": 120955340, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.691221", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.553G>T", "protein_change": "p.Gly185Cys", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1169" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2512/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2512/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2512/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2512/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2512/?format=api" } }, { "type": "SmallVariant", "id": "2514", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 6.763e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001496, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.387455, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121747954, "genomic_position_hg38": 120990378, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.703281", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.4464G>T", "protein_change": "p.Lys1488Phe", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1170" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2514/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2514/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2514/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2514/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2514/?format=api" } }, { "type": "SmallVariant", "id": "3164", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.755959, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121732606, "genomic_position_hg38": 120975030, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:59.467407", "ref_allele": "C", "alt_allele": "G", "cdna_change": "c.1289C>G", "protein_change": "p.Ala430Gly", "transcript_id": "NM_005270", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1511" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3164/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3164/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3164/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3164/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3164/?format=api" } }, { "type": "SmallVariant", "id": "3199", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0023, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0005995, "gnomad_AFR_maf": 0.006309, "gnomad_AMR_maf": 0.0009562, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001178, "gnomad_OTH_maf": 0.0003292, "gnomad_SAS_maf": 6.537e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.258477, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121747018, "genomic_position_hg38": 120989442, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:59.675475", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.3528G>T", "protein_change": "p.Gln1176His", "transcript_id": "NM_005270", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1524" }, { "type": "Combination", "id": "OLI1558" }, { "type": "Combination", "id": "OLI1746" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3199/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3199/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3199/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3199/gene/?format=api" }, "data": { "type": "Gene", "id": "GLI2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3199/?format=api" } }, { "type": "SmallVariant", "id": "3201", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.0002261, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0005475, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 6.553e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.966e-05, "gnomad_OTH_maf": 0.0005686, "gnomad_SAS_maf": 0.0009812, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": -0.183201, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 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