Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/GDNF/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "17",
            "attributes": {
                "gene_relationship": [
                    "Affecting the same tissue",
                    "Directly interacting",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [
                    "(GDNF, RET)"
                ],
                "common_pathways": [
                    "MAPK family signaling cascades",
                    "Nervous system development",
                    "Calcium signaling pathway",
                    "RET signaling",
                    "Axon guidance",
                    "RAF/MAP kinase cascade",
                    "Developmental Biology",
                    "Signal Transduction"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:00:45.869803"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI021"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/17/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/17/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "GDNF"
                        },
                        {
                            "type": "Gene",
                            "id": "RET"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/17/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/17/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/17/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "387",
            "attributes": {
                "gene_relationship": [
                    "Directly interacting",
                    "Indirectly interacting",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:05.841376"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI575"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/387/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/387/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 6
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CHD7"
                        },
                        {
                            "type": "Gene",
                            "id": "DENND1A"
                        },
                        {
                            "type": "Gene",
                            "id": "GDNF"
                        },
                        {
                            "type": "Gene",
                            "id": "GLI2"
                        },
                        {
                            "type": "Gene",
                            "id": "NR5A1"
                        },
                        {
                            "type": "Gene",
                            "id": "SOX30"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/387/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/387/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/387/?format=api"
            }
        }
    ]
}