Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/FEZF1/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "2686", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 4.233e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 9.363e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.290734, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121942107, "genomic_position_hg38": 122302053, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.630732", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1372C>T", "protein_change": "p.Pro458Ser", "transcript_id": "NM_001024613.4", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1274" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2686/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2686/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2686/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2686/gene/?format=api" }, "data": { "type": "Gene", "id": "FEZF1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2686/?format=api" } }, { "type": "SmallVariant", "id": "2689", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.977e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.791e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.494317, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121943770, "genomic_position_hg38": 122303716, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.649821", "ref_allele": "A", "alt_allele": "T", "cdna_change": "c.722T>A", "protein_change": "p.Ile241Asn", "transcript_id": "NM_001024613.4", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1275" }, { "type": "Combination", "id": "OLI1299" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2689/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2689/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2689/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2689/gene/?format=api" }, "data": { "type": "Gene", "id": "FEZF1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2689/?format=api" } }, { "type": "SmallVariant", "id": "2718", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.728306, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121944110, "genomic_position_hg38": 122304056, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.822787", "ref_allele": "T", "alt_allele": "G", "cdna_change": "c.382A>C", "protein_change": "p.Lys128Gln", "transcript_id": "NM_001024613.4", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1293" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2718/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2718/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2718/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2718/gene/?format=api" }, "data": { "type": "Gene", "id": "FEZF1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2718/?format=api" } }, { "type": "SmallVariant", "id": "2724", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0016, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.006, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.005817, "gnomad_AFR_maf": 0.001057, "gnomad_AMR_maf": 0.002106, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.013, "gnomad_NFE_maf": 0.008066, "gnomad_OTH_maf": 0.005977, "gnomad_SAS_maf": 0.004541, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.558951, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121944239, "genomic_position_hg38": 122304185, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.859061", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.253A>G", "protein_change": "p.Ser85Gly", "transcript_id": "NM_001024613.4", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1296" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2724/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2724/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2724/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2724/gene/?format=api" }, "data": { "type": "Gene", "id": "FEZF1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2724/?format=api" } }, { "type": "SmallVariant", "id": "2821", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.591e-05, "gnomad_AFR_maf": 0.0001232, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0001087, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.593494, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121943728, "genomic_position_hg38": 122303674, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:57.441480", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.614C>T", "protein_change": "p.Ala205Val", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1336" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2821/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2821/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2821/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2821/gene/?format=api" }, "data": { "type": "Gene", "id": "FEZF1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2821/?format=api" } }, { "type": "SmallVariant", "id": "3323", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0041, "gnomad_maf": 0.0005665, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 5.789e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 5.445e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001943, "gnomad_OTH_maf": 0.0003271, "gnomad_SAS_maf": 0.003758, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.505438, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 121943939, "genomic_position_hg38": 122303885, "chromosome": "7", "annotation_flag": null, "lastmodified": "2023-06-06T16:58:00.429107", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.553T>C", "protein_change": "p.Phe185Leu", "transcript_id": "NM_001024613", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1575" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3323/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3323/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3323/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3323/gene/?format=api" }, "data": { "type": "Gene", "id": "FEZF1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3323/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "Variant serializers": [ "SmallVariantSerializer", "CopyNumberVariantSerializer" ], "size": 6 } }