Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/EXO1/?format=api
{ "data": { "type": "Gene", "id": "EXO1", "attributes": { "go_molecular_function": [ "['RNA-DNA hybrid ribonuclease activity', 'chromatin binding', 'exonuclease activity', \"5'-3' exodeoxyribonuclease activity\", 'DNA binding', \"5'-flap endonuclease activity\", \"5'-3' exonuclease activity\", \"single-stranded DNA 5'-3' exodeoxyribonuclease activity\", 'protein binding', 'metal ion binding', \"double-stranded DNA 5'-3' exodeoxyribonuclease activity\", 'flap endonuclease activity']" ], "pathway_id": [ "kegg_path:hsa03430", "R-HSA-1640170", "R-HSA-212436", "R-HSA-3700989", "R-HSA-5358508", "R-HSA-5358565", "R-HSA-5358606", "R-HSA-5633007", "R-HSA-5685938", "R-HSA-5685942", "R-HSA-5693532", "R-HSA-5693537", "R-HSA-5693538", "R-HSA-5693554", "R-HSA-5693567", "R-HSA-5693568", "R-HSA-5693579", "R-HSA-5693607", "R-HSA-5693616", "R-HSA-6804756", "R-HSA-69473", "R-HSA-69481", "R-HSA-69620", "R-HSA-73857", "R-HSA-73894", "R-HSA-74160" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "Q9UQ84", "ensembl_id": "None", "entrez_id": "ENSG00000174371", "chromosome_number": "1" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "552" }, { "type": "SmallVariant", "id": "2616" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EXO1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EXO1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "188" }, { "type": "GeneCombination", "id": "869" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EXO1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EXO1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/EXO1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.689078", "status": "CU", "curator": null, "submitter": "cnachteg" } }