Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/ERCC2/?format=api
{ "data": { "type": "Gene", "id": "ERCC2", "attributes": { "go_molecular_function": [ "4 iron, 4 sulfur cluster binding", "ATP hydrolysis activity", "nucleotide binding", "DNA binding", "hydrolase activity", "iron-sulfur cluster binding", "helicase activity", "metal ion binding" ], "pathway_id": [ "R-HSA-167169", "R-HSA-5250941", "R-HSA-75955", "R-HSA-162599", "R-HSA-5696399", "R-HSA-113418", "R-HSA-1643685", "R-HSA-6781827", "R-HSA-76042", "R-HSA-167152", "R-HSA-73894", "R-HSA-212165", "R-HSA-112382", "R-HSA-167246", "R-HSA-6782135", "R-HSA-72086", "R-HSA-73776", "R-HSA-212436", "R-HSA-2564830", "R-HSA-3700989", "R-HSA-5663205", "R-HSA-73772", "R-HSA-73779", "R-HSA-5696400", "R-HSA-6782210", "R-HSA-74160", "R-HSA-75953", "R-HSA-162587", "R-HSA-167161", "R-HSA-73854", "kegg_path:hsa03022", "R-HSA-167160", "R-HSA-8953854", "R-HSA-77075", "R-HSA-6796648", "R-HSA-73863", "R-HSA-5696395", "R-HSA-167162", "R-HSA-1430728", "R-HSA-73857", "R-HSA-73762", "R-HSA-167158", "kegg_path:hsa03420", "R-HSA-167200", "R-HSA-427413", "R-HSA-6781823", "R-HSA-674695", "R-HSA-162906", "R-HSA-5696398", "R-HSA-167172", "R-HSA-73864" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "P18074", "ensembl_id": "ENSG00000104884", "entrez_id": "2068", "chromosome_number": "19" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1506" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ERCC2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ERCC2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "484" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ERCC2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ERCC2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ERCC2/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.983232", "status": "CU", "curator": null, "submitter": "cnachteg" } }