Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/COL4A5/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "71", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 2.08242, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 107834464, "genomic_position_hg38": 108591234, "chromosome": "X", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:40.943092", "ref_allele": "A", "alt_allele": "T", "cdna_change": "c.1339+3A>T", "protein_change": null, "transcript_id": "NM_033380.3", "dbsnp_id": "NA", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI033" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/71/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/71/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/71/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/71/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/71/?format=api" } }, { "type": "SmallVariant", "id": "277", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 8.743e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001959, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001486 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.36709, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107842023, "genomic_position_hg38": 108598793, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.153289", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1871G>A", "protein_change": "p.Gly624Asp", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI133" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/277/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/277/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/277/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/277/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/277/?format=api" } }, { "type": "SmallVariant", "id": "315", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.164355, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107863584, "genomic_position_hg38": 108620354, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.377425", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2605G>A", "protein_change": "p.Gly869Arg", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI156" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/315/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/315/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/315/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/315/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/315/?format=api" } }, { "type": "SmallVariant", "id": "836", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0079, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0314, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0084, "gnomad_maf": 0.003602, "gnomad_AFR_maf": 0.0005329, "gnomad_AMR_maf": 0.0001825, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.03676, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.227e-05, "gnomad_OTH_maf": 0.003104, "gnomad_SAS_maf": 0.006503, "ESP_AA_maf": 0.0005215, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.902127, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 107865996, "genomic_position_hg38": 108622766, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.502708", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.2858G>T", "protein_change": "p.Gly953Val", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI383" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/836/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/836/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/836/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/836/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/836/?format=api" } }, { "type": "SmallVariant", "id": "838", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.119746, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107842083, "genomic_position_hg38": 108598853, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.515632", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1931G>A", "protein_change": "p.Gly644Asp", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI384" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/838/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/838/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/838/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/838/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/838/?format=api" } }, { "type": "SmallVariant", "id": "840", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.753259, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107924159, "genomic_position_hg38": 108680929, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.528827", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.4042G>A", "protein_change": "p.Gly1348Arg", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI385" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/840/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/840/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/840/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/840/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/840/?format=api" } }, { "type": "SmallVariant", "id": "843", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.214777, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107845124, "genomic_position_hg38": 108601894, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.548461", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.2051G>T", "protein_change": "p.Gly684Val", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI386" }, { "type": "Combination", "id": "OLI387" }, { "type": "Combination", "id": "OLI388" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/843/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/843/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/843/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/843/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/843/?format=api" } }, { "type": "SmallVariant", "id": "1071", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 4.067553, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107844634, "genomic_position_hg38": 108601404, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.950171", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.1960G>T", "protein_change": "p.Asp654Tyr", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI504" }, { "type": "Combination", "id": "OLI916" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1071/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1071/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1071/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1071/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1071/?format=api" } }, { "type": "SmallVariant", "id": "1093", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.036812, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 107865087, "genomic_position_hg38": 108621857, "chromosome": "X", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:47.087929", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2732G>A", "protein_change": "p.Gly911Glu", "transcript_id": "NM_000495.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI516" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1093/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1093/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1093/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1093/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1093/?format=api" } }, { "type": "SmallVariant", "id": "2877", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": null, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 107834868, "genomic_position_hg38": 108591638, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:57.770986", "ref_allele": "AGT", "alt_allele": "A", "cdna_change": "c.1417_1418del", "protein_change": "p.Val473GlufsTer3", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1373" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2877/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2877/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2877/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2877/gene/?format=api" }, "data": { "type": "Gene", "id": "COL4A5" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2877/?format=api" } }, { "type": "SmallVariant", "id": "2879", "attributes": { "frequencies": { 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