Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/CELSR1/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "3114", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "-", "pp2_hvar_prediction": "-", "cadd_prediction": null, "mutationtaster_prediction": "-" }, "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "22", "annotation_flag": null, "lastmodified": "2023-05-16T12:02:59.807942", "ref_allele": null, "alt_allele": null, "cdna_change": "c.3544+23292_23323del", "protein_change": null, "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1477" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3114/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3114/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3114/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3114/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3114/?format=api" } }, { "type": "SmallVariant", "id": "1073", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0001281, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 9.972e-05, "gnomad_EAS_maf": 0.0005442, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001774, "gnomad_OTH_maf": 0.0001637, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0002326 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.869651, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46930763, "genomic_position_hg38": 46534866, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.962810", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2305C>T", "protein_change": "p.Arg769Trp", "transcript_id": "NM_014246.1", "dbsnp_id": "rs201601181", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI505" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1073/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1073/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1073/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1073/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1073/?format=api" } }, { "type": "SmallVariant", "id": "1075", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.003, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0002723, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.003612, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0001688, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.951363, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46760416, "genomic_position_hg38": 46364519, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.975298", "ref_allele": "C", "alt_allele": "G", "cdna_change": "c.8772G>C", "protein_change": "p.Gln2924His", "transcript_id": "NM_014246.1", "dbsnp_id": "rs200116798", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI506" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1075/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1075/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1075/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1075/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1075/?format=api" } }, { "type": "SmallVariant", "id": "1077", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 1.195e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0001632, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.680433, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46929704, "genomic_position_hg38": 46533807, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.987782", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.3364G>A", "protein_change": "p.Gly1122Ser", "transcript_id": "NM_014246.1", "dbsnp_id": "rs200363699", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI507" }, { "type": "Combination", "id": "OLI508" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1077/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1077/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1077/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1077/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1077/?format=api" } }, { "type": "SmallVariant", "id": "1081", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, "KGP_genomes_AFR_maf": 0.0015, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.001, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 8.376e-05, "gnomad_AFR_maf": 0.0007424, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.000272, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.766e-05, "gnomad_OTH_maf": 0.0001633, "gnomad_SAS_maf": 3.267e-05, "ESP_AA_maf": 0.001362, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.825758, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46929899, "genomic_position_hg38": 46534002, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:47.012873", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.3169C>T", "protein_change": "p.Arg1057Cys", "transcript_id": "NM_014246.1", "dbsnp_id": "rs148349145", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI510" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1081/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1081/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1081/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1081/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1081/?format=api" } }, { "type": "SmallVariant", "id": "1481", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.995e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 3.267e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 4.196815, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 46930208, "genomic_position_hg38": 46534311, "chromosome": "22", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:49.427982", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2860C>T", "protein_change": "p.Arg954Cys", "transcript_id": "NM_014246.4", "dbsnp_id": "rs772804547", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI684" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1481/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1481/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1481/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1481/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1481/?format=api" } }, { "type": "SmallVariant", "id": "1486", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 8e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 6.537e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.685217, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46761223, "genomic_position_hg38": 46365326, "chromosome": "22", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:49.459306", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.8459A>G", "protein_change": "p.Tyr2820Cys", "transcript_id": "NM_014246.4", "dbsnp_id": "rs773366645", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI686" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1486/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1486/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1486/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1486/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1486/?format=api" } }, { "type": "SmallVariant", "id": "1517", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 2.41e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.895e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 4.473e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.888686, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46785380, "genomic_position_hg38": 46389483, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.641490", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.6362G>A", "protein_change": "p.Arg2121His", "transcript_id": "NM_014246.1", "dbsnp_id": "rs765148329", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI698" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1517/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1517/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1517/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1517/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1517/?format=api" } }, { "type": "SmallVariant", "id": "1552", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 2.454e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0001006, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 4.554e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001164 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.928894, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 46760121, "genomic_position_hg38": 46364224, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.859559", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.8807C>T", "protein_change": "p.Pro2936Leu", "transcript_id": "NM_014246.1", "dbsnp_id": "rs201509338", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI710" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1552/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1552/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1552/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1552/gene/?format=api" }, "data": { "type": "Gene", "id": "CELSR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1552/?format=api" } }, { "type": "SmallVariant", "id": "1630", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.717145, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 46772993, "genomic_position_hg38": 46377096, "chromosome": "22", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:50.350483", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.7549G>A", "protein_change": "p.Val2517Met", "transcript_id": "NM_014246.1", "dbsnp_id": "rs1261513383", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI738" }, { "type": "Combination", "id": "OLI749" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1630/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1630/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1630/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1630/gene/?format=api" }, 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