Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/CCDC141/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "769", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0006, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.003, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 6.399e-05, "gnomad_AFR_maf": 6.26e-05, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0008182, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 3.286095, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179701727, "genomic_position_hg38": 178837000, "chromosome": "2", "annotation_flag": "manually_corrected", "lastmodified": "2023-06-06T16:57:45.104302", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.4219C>A", "protein_change": "p.Gln1407Lys", "transcript_id": "NM_173648.4", "dbsnp_id": "rs186697492", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI353" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/769/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/769/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/769/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/769/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/769/?format=api" } }, { "type": "SmallVariant", "id": "1417", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.198e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 5.79e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.851e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -0.764513, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179702195, "genomic_position_hg38": 178837468, "chromosome": "2", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:49.003770", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.3751G>T", "protein_change": "p.Val1251Leu", "transcript_id": "NM_173648.3", "dbsnp_id": "rs888332352", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI651" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1417/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1417/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1417/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1417/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1417/?format=api" } }, { "type": "SmallVariant", "id": "2578", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0357, "KGP_genomes_AFR_maf": 0.0023, "KGP_genomes_AMR_maf": 0.0735, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.1014, "KGP_genomes_SAS_maf": 0.0235, "gnomad_maf": 0.06032, "gnomad_AFR_maf": 0.01345, "gnomad_AMR_maf": 0.04904, "gnomad_ASJ_maf": 0.05217, "gnomad_EAS_maf": 0.0001097, "gnomad_FIN_maf": 0.07249, "gnomad_NFE_maf": 0.08669, "gnomad_OTH_maf": 0.07247, "gnomad_SAS_maf": 0.02747, "ESP_AA_maf": 0.02339, "ESP_EA_maf": 0.09016 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.514477, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179721046, "genomic_position_hg38": 178856319, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.961189", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.2803C>T", "protein_change": "p.Arg935Trp", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1213" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2578/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2578/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2578/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2578/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2578/?format=api" } }, { "type": "SmallVariant", "id": "2890", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0016, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0043, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.004, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.004465, "gnomad_AFR_maf": 0.001322, "gnomad_AMR_maf": 0.002284, "gnomad_ASJ_maf": 0.009604, "gnomad_EAS_maf": 9.513e-05, "gnomad_FIN_maf": 0.003674, "gnomad_NFE_maf": 0.007634, "gnomad_OTH_maf": 0.005366, "gnomad_SAS_maf": 0.0003113, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.436302, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179699124, "genomic_position_hg38": 178834397, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:57.849825", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.4369G>A", "protein_change": "p.Val1457Ile", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1379" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2890/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2890/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2890/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2890/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2890/?format=api" } }, { "type": "SmallVariant", "id": "2892", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.464993, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179912054, "genomic_position_hg38": 179047327, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:57.861813", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.182A>G", "protein_change": "p.Lys61Arg", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1380" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2892/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2892/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2892/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2892/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2892/?format=api" } }, { "type": "SmallVariant", "id": "2915", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.001, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.001497, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0001159, "gnomad_ASJ_maf": 0.002581, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.007576, "gnomad_NFE_maf": 0.001488, "gnomad_OTH_maf": 0.002124, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.349455, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179718301, "genomic_position_hg38": 178853574, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:58.000929", "ref_allele": "T", "alt_allele": "A", "cdna_change": "c.3111A>T", "protein_change": "p.Lys1037Asn", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1389" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2915/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2915/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2915/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2915/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2915/?format=api" } }, { "type": "SmallVariant", "id": "2922", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0022, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0058, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.005, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.003484, "gnomad_AFR_maf": 0.001118, "gnomad_AMR_maf": 0.002846, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.004451, "gnomad_NFE_maf": 0.005715, "gnomad_OTH_maf": 0.002946, "gnomad_SAS_maf": 0.0008851, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.991564, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179751485, "genomic_position_hg38": 178886758, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:58.043361", "ref_allele": "T", "alt_allele": "G", "cdna_change": "c.1521A>C", "protein_change": "p.Gln507His", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1392" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2922/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2922/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2922/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2922/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2922/?format=api" } }, { "type": "SmallVariant", "id": "2950", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.976e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.000925, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -1.01474, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179742788, "genomic_position_hg38": 178878061, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:58.213088", "ref_allele": "T", "alt_allele": "A", "cdna_change": "c.1802A>T", "protein_change": "p.His601Leu", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1404" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2950/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2950/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2950/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2950/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2950/?format=api" } }, { "type": "SmallVariant", "id": "3014", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.974e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.765e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.176414, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179701910, "genomic_position_hg38": 178837183, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:58.604804", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.4036C>T", "protein_change": "p.Arg1346Trp", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1431" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3014/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3014/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3014/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3014/gene/?format=api" }, "data": { "type": "Gene", "id": "CCDC141" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3014/?format=api" } }, { "type": "SmallVariant", "id": "3165", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0001078, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0001158, "gnomad_ASJ_maf": 0.000199, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001416, "gnomad_OTH_maf": 0.0003274, "gnomad_SAS_maf": 9.801e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.770712, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179702164, "genomic_position_hg38": 178837437, "chromosome": "2", 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