Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/AR/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "580", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": null, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "X", "annotation_flag": "not_found_in_databases", "lastmodified": "2021-10-18T11:00:54.768809", "ref_allele": null, "alt_allele": null, "cdna_change": "c.1995delTGAAGGCTATGAATGTCinsCAGAA", "protein_change": "p.666delGluGlyTyrGluCysGlninsArgLys", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "insertion" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI299" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/580/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/580/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/580/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/580/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/580/?format=api" } }, { "type": "CopyNumberVariant", "id": "2184", "attributes": { "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "X", "annotation_flag": "cnv", "lastmodified": "2022-08-04T14:15:20.577254", "location": "exon2_8", "sequence": "exon2_8", "number_of_repeats": null, "type_cnv": "deletion" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1006" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2184/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2184/combinations/?format=api" } }, "gene_name": { "data": { "type": "Gene", "id": "AR" }, "links": { "related": "https://olida.ibsquare.be/api/genes/AR/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2184/?format=api" } }, { "type": "SmallVariant", "id": "646", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.001129, "gnomad_AFR_maf": 0.0001677, "gnomad_AMR_maf": 0.0001549, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.000408, "gnomad_NFE_maf": 0.002433, "gnomad_OTH_maf": 0.0002398, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.002527 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.34997, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 66931295, "genomic_position_hg38": 67711453, "chromosome": "X", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:44.306699", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.341C>A", "protein_change": "p.Ala114Asp", "transcript_id": "NM_001011645.3", "dbsnp_id": "rs1800053", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI329" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/646/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/646/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/646/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/646/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/646/?format=api" } }, { "type": "SmallVariant", "id": "2159", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.133302, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 66943556, "genomic_position_hg38": 67723714, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.583535", "ref_allele": "T", "alt_allele": "G", "cdna_change": "c.2636T>G", "protein_change": "p.Phe879Cys", "transcript_id": "NM_000044.6", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI996" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2159/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2159/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2159/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2159/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2159/?format=api" } }, { "type": "SmallVariant", "id": "2164", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 6.616492, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 66863249, "genomic_position_hg38": 67643407, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.610007", "ref_allele": "G", "alt_allele": "C", "cdna_change": "c.1768G>C", "protein_change": "p.Gly590Arg", "transcript_id": "NM_000044.6", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI997" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2164/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2164/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2164/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2164/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2164/?format=api" } }, { "type": "SmallVariant", "id": "2168", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.636e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0001443, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.222e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.755055, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 66765872, "genomic_position_hg38": 67546030, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.633052", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.884T>C", "protein_change": "p.Leu295Pro", "transcript_id": "NM_000044.6", "dbsnp_id": "rs745333161|", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI998" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2168/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2168/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2168/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2168/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2168/?format=api" } }, { "type": "SmallVariant", "id": "2171", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 1.21221, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 66943587, "genomic_position_hg38": 67723745, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.654348", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.2667C>T", "protein_change": "p.Ser889=", "transcript_id": "NM_000044.6", "dbsnp_id": "rs137852594", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI999" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2171/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2171/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2171/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2171/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2171/?format=api" } }, { "type": "SmallVariant", "id": "2173", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.327852, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 66942740, "genomic_position_hg38": 67722898, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.668361", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.2521C>T", "protein_change": "p.Arg841Cys", "transcript_id": "NM_000044.6", "dbsnp_id": "rs137852577", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1000" }, { "type": "Combination", "id": "OLI1001" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2173/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2173/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2173/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2173/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2173/?format=api" } }, { "type": "SmallVariant", "id": "2175", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0003, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0013, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 1.401e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 3.383e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.743279, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 66766163, "genomic_position_hg38": 67546321, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.682330", "ref_allele": "C", "alt_allele": "G", "cdna_change": "c.1175C>G", "protein_change": "p.Pro392Arg", "transcript_id": "NM_000044.6", "dbsnp_id": "rs773996740", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1001" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2175/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2175/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2175/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2175/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2175/?format=api" } }, { "type": "SmallVariant", "id": "2177", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0005, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0026, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0006634, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.008287, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0002446, "gnomad_SAS_maf": 0.0001198, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.768754, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 66765516, "genomic_position_hg38": 67545674, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.695899", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.528C>A", "protein_change": "p.Ser176Arg", "transcript_id": "NM_000044.6", "dbsnp_id": "rs777131133", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1002" }, { "type": "Combination", "id": "OLI1003" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2177/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2177/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2177/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2177/gene/?format=api" }, "data": { "type": "Gene", "id": "AR" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2177/?format=api" } }, { "type": "SmallVariant", "id": "2180", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.104e-05, "gnomad_AFR_maf": 0.0001521, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0002608, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.743217, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 66943532, "genomic_position_hg38": 67723690, "chromosome": "X", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:53.716130", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.2612C>T", "protein_change": 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