Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/ALOX15/?format=api
{ "data": { "type": "Gene", "id": "ALOX15", "attributes": { "go_molecular_function": [ "linoleate 13S-lipoxygenase activity", "protein binding", "arachidonate 15-lipoxygenase activity", "arachidonate 12(S)-lipoxygenase activity", "iron ion binding", "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen", "phosphatidylinositol-4,5-bisphosphate binding" ], "pathway_id": [ "R-HSA-9023661", "R-HSA-9025106", "kegg_path:hsa04217", "R-HSA-168256", "kegg_path:hsa00591", "kegg_path:hsa04216", "R-HSA-8978868", "R-HSA-9026286", "kegg_path:hsa01100", "R-HSA-9018681", "R-HSA-2142691", "R-HSA-1280215", "R-HSA-9025094", "R-HSA-1430728", "R-HSA-9018677", "R-HSA-9018896", "R-HSA-6785807", "R-HSA-9018678", "kegg_path:hsa04726", "R-HSA-2142770", "R-HSA-9018679", "R-HSA-449147", "R-HSA-2142712", "R-HSA-2142753", "R-HSA-9018683", "R-HSA-556833", "kegg_path:hsa00590" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "P16050", "ensembl_id": "ENSG00000161905", "entrez_id": "246", "chromosome_number": "17" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "645" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ALOX15/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ALOX15/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "217" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ALOX15/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ALOX15/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ALOX15/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.509598", "status": "CU", "curator": null, "submitter": "cnachteg" } }