Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/891/combinations/?format=api&ordering=oligogenic_effect
{ "data": [ { "type": "Combination", "id": "OLI313", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.644349" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI313/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI313/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "606" }, { "type": "SmallVariant", "id": "607" }, { "type": "SmallVariant", "id": "608" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI313/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI313/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI313/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI313/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI313/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI313/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "206" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI313/?format=api" } }, { "type": "Combination", "id": "OLI314", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.660105" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI314/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI314/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "609" }, { "type": "SmallVariant", "id": "610" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI314/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI314/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI314/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI314/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI314/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI314/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "207" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI314/?format=api" } }, { "type": "Combination", "id": "OLI453", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Moroccan", "lastmodified": "2021-11-16T17:59:45.681783" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI453/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI453/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "966" }, { "type": "SmallVariant", "id": "967" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI453/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI453/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "759" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI453/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI453/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI453/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI453/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "310" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI453/?format=api" } }, { "type": "Combination", "id": "OLI306", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.531048" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI306/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI306/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "592" }, { "type": "SmallVariant", "id": "593" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI306/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI306/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI306/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI306/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI306/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI306/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "204" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI306/?format=api" } }, { "type": "Combination", "id": "OLI312", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "True Digenic", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.624379" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI312/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI312/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "604" }, { "type": "SmallVariant", "id": "605" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI312/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI312/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI312/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI312/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI312/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI312/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "206" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI312/?format=api" } }, { "type": "Combination", "id": "OLI307", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 2 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "True Digenic", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.546708" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI307/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI307/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "594" }, { "type": "SmallVariant", "id": "595" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI307/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI307/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI307/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI307/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI307/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI307/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "204" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI307/?format=api" } }, { "type": "Combination", "id": "OLI315", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "True Digenic", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.675872" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI315/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI315/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "362" }, { "type": "SmallVariant", "id": "611" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI315/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI315/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI315/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI315/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI315/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI315/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "208" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI315/?format=api" } }, { "type": "Combination", "id": "OLI419", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Japanese", "lastmodified": "2021-11-16T17:59:45.103358" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI419/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI419/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "897" }, { "type": "SmallVariant", "id": "898" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI419/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI419/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "731" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI419/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI419/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI419/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI419/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "204" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI419/?format=api" } }, { "type": "Combination", "id": "OLI455", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:45.713478" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI455/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI455/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "970" }, { "type": "SmallVariant", "id": "971" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI455/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI455/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "757" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI455/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI455/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI455/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI455/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "311" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI455/?format=api" } }, { "type": "Combination", "id": "OLI1249", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM305390", "OMIM601813", "OMIM613310", "OMIM616468", "OMIM605750", "OMIM133780", "OMIM617572" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:42.626581" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "891" } ], "links": { "self": 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