Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/88661/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI521", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Turkish", "lastmodified": "2021-11-16T17:59:46.864696" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI521/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI521/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1104" }, { "type": "SmallVariant", "id": "1105" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI521/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI521/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "683" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI521/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI521/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI521/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI521/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "361" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI521/?format=api" } }, { "type": "Combination", "id": "OLI1641", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Dual Molecular Diagnosis", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2024-02-29T15:02:26.026497" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1641/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1641/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3450" }, { "type": "CopyNumberVariant", "id": "3451" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1641/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1641/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "975" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1641/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1641/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1641/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1641/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1160" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1641/?format=api" } }, { "type": "Combination", "id": "OLI1642", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2024-02-29T15:02:26.107642" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1642/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1642/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3452" }, { "type": "SmallVariant", "id": "3453" }, { "type": "SmallVariant", "id": "3454" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1642/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1642/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "975" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1642/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1642/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1642/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1642/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1161" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1642/?format=api" } }, { "type": "Combination", "id": "OLI1733", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.353901" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1733/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1733/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3675" }, { "type": "SmallVariant", "id": "3676" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1733/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1733/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "992" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1733/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1733/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1733/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1733/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1240" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1733/?format=api" } }, { "type": "Combination", "id": "OLI1734", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.407876" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1734/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1734/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3677" }, { "type": "SmallVariant", "id": "3678" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1734/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1734/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "992" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1734/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1734/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1734/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1734/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1241" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1734/?format=api" } }, { "type": "Combination", "id": "OLI1735", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.474310" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1735/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1735/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3679" }, { "type": "SmallVariant", "id": "3680" }, { "type": "SmallVariant", "id": "3678" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1735/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1735/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "992" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1735/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1735/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1735/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1735/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1242" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1735/?format=api" } }, { "type": "Combination", "id": "OLI1736", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.528455" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1736/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1736/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3681" }, { "type": "SmallVariant", "id": "3682" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1736/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1736/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "992" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1736/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1736/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1736/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1736/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1243" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1736/?format=api" } }, { "type": "Combination", "id": "OLI1737", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM616270", "OMIM612529", "OMIM130900", "OMIM614832", "OMIM204700", "OMIM616221", "OMIM301200", "OMIM204650", "OMIM104510", "OMIM104500", "OMIM617217", "OMIM104530", "OMIM301201", "OMIM613211", "OMIM615887" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.584536" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "88661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1737/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1737/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3683" }, { "type": "SmallVariant", "id": "3684" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1737/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1737/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "992" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1737/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1737/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1737/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1737/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1244" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1737/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte 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