Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/475/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI244", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM617622", "OMIM614464", "OMIM617120", "OMIM616654", "OMIM614615", "OMIM616784", "OMIM612291", "OMIM614970", "OMIM615636", "OMIM617121", "OMIM614173", "OMIM614424", "OMIM616781", "OMIM213300", "OMIM610688", "OMIM618161", "OMIM616490", "OMIM617761" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:41.500030" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "475" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI244/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI244/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "476" }, { "type": "SmallVariant", "id": "477" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI244/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI244/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "647" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI244/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI244/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI244/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI244/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "159" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI244/?format=api" } }, { "type": "Combination", "id": "OLI245", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM617622", "OMIM614464", "OMIM617120", "OMIM616654", "OMIM614615", "OMIM616784", "OMIM612291", "OMIM614970", "OMIM615636", "OMIM617121", "OMIM614173", "OMIM614424", "OMIM616781", "OMIM213300", "OMIM610688", "OMIM618161", "OMIM616490", "OMIM617761" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:41.516141" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "475" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI245/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI245/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "478" }, { "type": "SmallVariant", "id": "479" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI245/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI245/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "647" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI245/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI245/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI245/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI245/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "160" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI245/?format=api" } }, { "type": "Combination", "id": "OLI246", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM617622", "OMIM614464", "OMIM617120", "OMIM616654", "OMIM614615", "OMIM616784", "OMIM612291", "OMIM614970", "OMIM615636", "OMIM617121", "OMIM614173", "OMIM614424", "OMIM616781", "OMIM213300", "OMIM610688", "OMIM618161", "OMIM616490", "OMIM617761" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:41.531996" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "475" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI246/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI246/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "480" }, { "type": "SmallVariant", "id": "481" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI246/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI246/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "647" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI246/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI246/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI246/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI246/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "161" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI246/?format=api" } }, { "type": "Combination", "id": "OLI247", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM617622", "OMIM614464", "OMIM617120", "OMIM616654", "OMIM614615", "OMIM616784", "OMIM612291", "OMIM614970", "OMIM615636", "OMIM617121", "OMIM614173", "OMIM614424", "OMIM616781", "OMIM213300", "OMIM610688", "OMIM618161", "OMIM616490", "OMIM617761" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:41.548100" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "475" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI247/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI247/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "482" }, { "type": "SmallVariant", "id": "483" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI247/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI247/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "647" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI247/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI247/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI247/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI247/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "161" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI247/?format=api" } }, { "type": "Combination", "id": "OLI640", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM617622", "OMIM614464", "OMIM617120", "OMIM616654", "OMIM614615", "OMIM616784", "OMIM612291", "OMIM614970", "OMIM615636", "OMIM617121", "OMIM614173", "OMIM614424", "OMIM616781", "OMIM213300", "OMIM610688", "OMIM618161", "OMIM616490", "OMIM617761" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:49.415360" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "475" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI640/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI640/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1385" }, { "type": "SmallVariant", "id": "1386" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI640/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI640/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "838" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI640/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI640/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI640/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI640/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "437" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI640/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 5 } }