Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/467/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI1242", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 3, "functional_final_metascore": 3, "final_manual": 2, "final_metascore": 2 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European", "lastmodified": "2023-05-16T12:02:42.026113" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "467" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1242/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1242/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2630" }, { "type": "SmallVariant", "id": "2631" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1242/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1242/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "931" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1242/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1242/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1242/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1242/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "875" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1242/?format=api" } }, { "type": "Combination", "id": "OLI1324", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:02:47.691991" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "467" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1324/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1324/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2775" }, { "type": "SmallVariant", "id": "2776" }, { "type": "SmallVariant", "id": "2777" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1324/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1324/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "945" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1324/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1324/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1324/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1324/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "928" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1324/?format=api" } }, { "type": "Combination", "id": "OLI1325", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:02:47.776078" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "467" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1325/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1325/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2778" }, { "type": "SmallVariant", "id": "2779" }, { "type": "SmallVariant", "id": "2780" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1325/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1325/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "945" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1325/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1325/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1325/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1325/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "929" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1325/?format=api" } }, { "type": "Combination", "id": "OLI402", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:44.831852" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "467" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI402/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI402/diseases/?format=api" } }, "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "864" }, { "type": "SmallVariant", "id": "865" }, { "type": "SmallVariant", "id": "866" }, { "type": "SmallVariant", "id": "867" }, { "type": "SmallVariant", "id": "868" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI402/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI402/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "844" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI402/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI402/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI402/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI402/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "269" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI402/?format=api" } }, { "type": "Combination", "id": "OLI960", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:13.177179" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "467" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI960/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI960/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2073" }, { "type": "SmallVariant", "id": "2074" }, { "type": "SmallVariant", "id": "2075" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI960/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI960/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "879" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI960/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI960/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI960/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI960/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "717" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI960/?format=api" } }, { "type": "Combination", "id": "OLI961", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:13.352247" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "467" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI961/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI961/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2076" }, { "type": "SmallVariant", "id": "2077" }, { "type": "SmallVariant", "id": "2078" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI961/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI961/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "879" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI961/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI961/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI961/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI961/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "718" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI961/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 6 } }