Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/402075/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI1472", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM109730", "OMIM614823" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:02:59.528826" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "402075" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1472/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1472/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3102" }, { "type": "SmallVariant", "id": "3103" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1472/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1472/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "963" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1472/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1472/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1472/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1472/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1040" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1472/?format=api" } }, { "type": "Combination", "id": "OLI1473", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM109730", "OMIM614823" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:02:59.584419" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "402075" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1473/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1473/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3104" }, { "type": "SmallVariant", "id": "3105" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1473/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1473/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "963" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1473/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1473/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1473/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1473/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1041" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1473/?format=api" } }, { "type": "Combination", "id": "OLI1742", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM109730", "OMIM614823" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.894082" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "402075" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1742/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1742/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3694" }, { "type": "SmallVariant", "id": "3695" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1742/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1742/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "997" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1742/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1742/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1742/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1742/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1249" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1742/?format=api" } }, { "type": "Combination", "id": "OLI1743", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM109730", "OMIM614823" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:33.952409" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "402075" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1743/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1743/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3696" }, { "type": "SmallVariant", "id": "3697" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1743/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1743/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "997" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1743/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1743/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1743/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1743/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1250" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1743/?format=api" } }, { "type": "Combination", "id": "OLI1744", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM109730", "OMIM614823" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2024-02-29T15:02:34.011009" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "402075" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1744/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1744/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3698" }, { "type": "SmallVariant", "id": "3699" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1744/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1744/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "997" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1744/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1744/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1744/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1744/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1251" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1744/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 5 } }