Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/36387/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI168", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM613863", "OMIM604233", "OMIM613060", "OMIM604403", "OMIM611277", "OMIM613828", "OMIM616172", "OMIM618482", "OMIM609800", "OMIM612279" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:40.232601" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "36387" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI168/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI168/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "338" }, { "type": "SmallVariant", "id": "339" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI168/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI168/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "743" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI168/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI168/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI168/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI168/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "119" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI168/?format=api" } }, { "type": "Combination", "id": "OLI557", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM613863", "OMIM611942", "OMIM604233", "OMIM613060", "OMIM600131", "OMIM604403", "OMIM611277", "OMIM613828", "OMIM612269", "OMIM616172", "OMIM607681", "OMIM611136", "OMIM618482", "OMIM609800", "OMIM612279" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Tunisian", "lastmodified": "2021-11-16T17:59:47.463085" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "36387" }, { "type": "Disease", "id": "64280" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI557/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI557/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1163" }, { "type": "SmallVariant", "id": "1164" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI557/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI557/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "818" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI557/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI557/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI557/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI557/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "373" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI557/?format=api" } }, { "type": "Combination", "id": "OLI559", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM617924", "OMIM604233", "OMIM608816", "OMIM611364", "OMIM611136", "OMIM618482", "OMIM609800", "OMIM611277", "OMIM613060", "OMIM614280", "OMIM607682", "OMIM612279", "OMIM613863", "OMIM254770", "OMIM604827", "OMIM604403", "OMIM613828", "OMIM607628", "OMIM616172" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Tunisian", "lastmodified": "2021-11-16T17:59:47.495922" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "36387" }, { "type": "Disease", "id": "307" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI559/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI559/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1167" }, { "type": "SmallVariant", "id": "1168" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI559/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI559/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "818" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI559/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI559/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI559/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI559/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "375" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI559/?format=api" } }, { "type": "Combination", "id": "OLI560", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM613863", "OMIM604233", "OMIM613060", "OMIM604403", "OMIM611277", "OMIM613828", "OMIM616172", "OMIM618482", "OMIM609800", "OMIM612279" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Tunisian", "lastmodified": "2021-11-16T17:59:47.511730" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "36387" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI560/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI560/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1169" }, { "type": "SmallVariant", "id": "1170" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI560/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI560/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "818" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI560/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI560/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI560/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI560/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "376" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI560/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 4 } }