Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/3109/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI1136", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:39.240220" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1136/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1136/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2445" }, { "type": "SmallVariant", "id": "2446" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1136/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1136/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1136/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1136/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1136/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1136/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "824" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1136/?format=api" } }, { "type": "Combination", "id": "OLI1137", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:39.365242" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1137/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1137/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2447" }, { "type": "SmallVariant", "id": "2448" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1137/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1137/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1137/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1137/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1137/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1137/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "825" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1137/?format=api" } }, { "type": "Combination", "id": "OLI1138", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:39.490271" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1138/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1138/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2449" }, { "type": "SmallVariant", "id": "2450" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1138/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1138/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1138/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1138/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1138/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1138/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "826" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1138/?format=api" } }, { "type": "Combination", "id": "OLI1139", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:39.665300" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1139/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1139/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2451" }, { "type": "SmallVariant", "id": "2452" }, { "type": "SmallVariant", "id": "2453" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1139/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1139/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1139/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1139/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1139/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1139/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "827" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1139/?format=api" } }, { "type": "Combination", "id": "OLI1140", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:39.790331" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1140/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1140/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2454" }, { "type": "SmallVariant", "id": "2455" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1140/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1140/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1140/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1140/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1140/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1140/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "828" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1140/?format=api" } }, { "type": "Combination", "id": "OLI1141", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:39.915400" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1141/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1141/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2456" }, { "type": "SmallVariant", "id": "2457" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1141/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1141/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1141/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1141/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1141/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1141/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "829" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1141/?format=api" } }, { "type": "Combination", "id": "OLI1142", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:40.090373" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1142/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1142/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2458" }, { "type": "SmallVariant", "id": "2459" }, { "type": "SmallVariant", "id": "2460" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1142/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1142/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1142/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1142/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1142/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1142/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "830" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1142/?format=api" } }, { "type": "Combination", "id": "OLI1143", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:40.232074" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1143/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1143/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2461" }, { "type": "SmallVariant", "id": "2462" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1143/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1143/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1143/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1143/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1143/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1143/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "831" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1143/?format=api" } }, { "type": "Combination", "id": "OLI1144", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM277000", "OMIM601076" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2022-08-04T14:15:40.357121" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3109" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1144/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1144/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2463" }, { "type": "SmallVariant", "id": "2464" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1144/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1144/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "914" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1144/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1144/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1144/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1144/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "832" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1144/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 9 } }