Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/217604/combinations/?format=api
https://olida.ibsquare.be/api/combinations/OLI068/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI068/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "134" }, { "type": "SmallVariant", "id": "135" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI068/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI068/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "610" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI068/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI068/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI068/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI068/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "48" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI068/?format=api" } }, { "type": "Combination", "id": "OLI235", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.351013" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "458" }, { "type": "SmallVariant", "id": "459" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "152" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/?format=api" } }, { "type": "Combination", "id": "OLI236", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.370673" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "452" }, { "type": "SmallVariant", "id": "453" }, { "type": "SmallVariant", "id": "460" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "150" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/?format=api" } }, { "type": "Combination", "id": "OLI416", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 2 }, "omim_id": [], "oligogenic_effect": "True Digenic", "status": "CU", "effect_predicted": false, "ethnicity": "Iranian", "lastmodified": "2021-11-16T17:59:45.055762" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI416/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI416/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "892" }, { "type": "SmallVariant", "id": "893" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI416/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI416/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "735" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI416/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI416/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI416/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI416/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "277" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI416/?format=api" } }, { "type": "Combination", "id": "OLI1326", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:47.852541" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1326/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1326/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2781" }, { "type": "SmallVariant", "id": "2782" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1326/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1326/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "946" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1326/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1326/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1326/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1326/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "930" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1326/?format=api" } }, { "type": "Combination", "id": "OLI1797", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:37.954450" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1797/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1797/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3760" }, { "type": "SmallVariant", "id": "3761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1797/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1797/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "1005" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1797/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1797/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1797/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1797/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1272" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1797/?format=api" } }, { "type": "Combination", "id": "OLI1798", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:38.012736" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1798/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1798/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3762" }, { "type": "SmallVariant", "id": "3763" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1798/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1798/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "1005" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1798/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1798/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1798/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1798/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1273" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1798/?format=api" } }, { "type": "Combination", "id": "OLI1799", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:38.065941" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1799/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1799/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3764" }, { "type": "SmallVariant", "id": "3765" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1799/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1799/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "1005" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1799/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1799/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1799/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1799/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1274" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1799/?format=api" } }, { "type": "Combination", "id": "OLI1800", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:38.111732" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1800/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1800/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3765" }, { "type": "SmallVariant", "id": "3766" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1800/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1800/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "1005" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1800/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1800/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1800/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1800/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1275" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1800/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 9 } }{ "data": [ { "type": "Combination", "id": "OLI068", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 2, "final_metascore": 2 }, "omim_id": [], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Middle eastern", "lastmodified": "2021-11-16T17:59:38.497585" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "