Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/158038/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI025", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:37.748940" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI025/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI025/diseases/?format=api" } }, "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "49" }, { "type": "SmallVariant", "id": "50" }, { "type": "SmallVariant", "id": "51" }, { "type": "SmallVariant", "id": "52" }, { "type": "SmallVariant", "id": "53" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI025/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI025/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "668" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI025/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI025/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI025/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI025/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "21" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI025/?format=api" } }, { "type": "Combination", "id": "OLI052", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.226759" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI052/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI052/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "102" }, { "type": "SmallVariant", "id": "103" }, { "type": "SmallVariant", "id": "104" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI052/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI052/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI052/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI052/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI052/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI052/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "36" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI052/?format=api" } }, { "type": "Combination", "id": "OLI053", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.242495" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI053/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI053/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "105" }, { "type": "SmallVariant", "id": "106" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI053/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI053/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI053/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI053/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI053/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI053/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "37" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI053/?format=api" } }, { "type": "Combination", "id": "OLI054", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.258022" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI054/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI054/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "107" }, { "type": "SmallVariant", "id": "108" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI054/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI054/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI054/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI054/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI054/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI054/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "38" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI054/?format=api" } }, { "type": "Combination", "id": "OLI055", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.278161" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI055/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI055/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "109" }, { "type": "SmallVariant", "id": "110" }, { "type": "SmallVariant", "id": "111" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI055/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI055/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI055/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI055/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI055/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI055/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "39" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI055/?format=api" } }, { "type": "Combination", "id": "OLI056", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.292536" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI056/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI056/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "112" }, { "type": "SmallVariant", "id": "113" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI056/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI056/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI056/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI056/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI056/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI056/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "40" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI056/?format=api" } }, { "type": "Combination", "id": "OLI057", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.308361" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI057/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI057/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "102" }, { "type": "SmallVariant", "id": "114" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI057/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI057/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI057/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI057/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI057/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI057/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "41" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI057/?format=api" } }, { "type": "Combination", "id": "OLI058", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.323696" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "158038" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI058/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI058/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "115" }, { "type": "SmallVariant", "id": "116" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI058/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI058/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "761" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI058/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI058/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI058/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI058/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "39" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI058/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 8 } }