Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/combinations/OLI412/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "274",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Directly interacting",
                    "Same pathway"
                ],
                "protein_interactions": [
                    "(MEFV, NLRP3)"
                ],
                "common_pathways": [
                    "NOD-like receptor signaling pathway",
                    "Infectious disease",
                    "Cell recruitment (pro-inflammatory response)",
                    "Disease",
                    "Immune System",
                    "Leishmania infection",
                    "The NLRP3 inflammasome",
                    "Inflammasomes",
                    "leucine rich repeat containing receptor (NLR) signaling pathways",
                    "Nucleotide-binding domain",
                    "Purinergic signaling in leishmaniasis infection",
                    "Innate Immune System"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:01:00.114104"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI411"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI412"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/274/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/274/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "MEFV"
                        },
                        {
                            "type": "Gene",
                            "id": "NLRP3"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/274/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/274/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/274/?format=api"
            }
        }
    ]
}