Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/variants/80/combinations/?format=api&ordering=combination_id
{ "data": [ { "type": "Combination", "id": "OLI037", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM602772", "OMIM610282", "OMIM614500", "OMIM618697", "OMIM613827", "OMIM617460", "OMIM618195", "OMIM618220", "OMIM300155", "OMIM616562", "OMIM613194", "OMIM613809", "OMIM612095", "OMIM609923", "OMIM300424", "OMIM613769", "OMIM615780", "OMIM613464", "OMIM180210", "OMIM604232", "OMIM614181", "OMIM268000", "OMIM613575", "OMIM268060", "OMIM616469", "OMIM617304", "OMIM608380", "OMIM615434", "OMIM180100", "OMIM600059", "OMIM600852", "OMIM613581", "OMIM268025", "OMIM610599", "OMIM618173", "OMIM180104", "OMIM604393", "OMIM617123", "OMIM610359", "OMIM600138", "OMIM612943", "OMIM613341", "OMIM611131", "OMIM613810", "OMIM613428", "OMIM613617", "OMIM600105", "OMIM312600", "OMIM613801", "OMIM612712", "OMIM613861", "OMIM606068", "OMIM616394", "OMIM615565", "OMIM617433", "OMIM612572", "OMIM600132", "OMIM615725", "OMIM616188", "OMIM613767", "OMIM614494", "OMIM400004", "OMIM601414", "OMIM618613", "OMIM617781", "OMIM615922", "OMIM613983", "OMIM300605", "OMIM607921", "OMIM613794", "OMIM180105", "OMIM614180", "OMIM612165", "OMIM615233", "OMIM613756", "OMIM608133", "OMIM602594", "OMIM312612", "OMIM601718", "OMIM613862", "OMIM300029", "OMIM616544", "OMIM618826", "OMIM618345", "OMIM613750", "OMIM613731", "OMIM613660", "OMIM613758", "OMIM613582", "OMIM617023", "OMIM609913" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:37.955499" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "791" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI037/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI037/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "79" }, { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "81" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI037/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI037/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "741" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI037/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI037/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI037/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI037/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "32" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI037/?format=api" } }, { "type": "Combination", "id": "OLI038", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM602772", "OMIM610282", "OMIM614500", "OMIM618697", "OMIM613827", "OMIM617460", "OMIM618195", "OMIM618220", "OMIM300155", "OMIM616562", "OMIM613194", "OMIM613809", "OMIM612095", "OMIM606874", "OMIM609923", "OMIM300424", "OMIM613769", "OMIM615780", "OMIM613464", "OMIM180210", "OMIM604232", "OMIM614181", "OMIM268000", "OMIM613575", "OMIM268060", "OMIM616469", "OMIM617304", "OMIM608380", "OMIM615434", "OMIM180100", "OMIM600059", "OMIM600852", "OMIM613581", "OMIM268025", "OMIM610599", "OMIM618173", "OMIM142623", "OMIM180104", "OMIM604393", "OMIM617123", "OMIM610359", "OMIM600138", "OMIM613712", "OMIM612943", "OMIM613341", "OMIM611131", "OMIM611644", "OMIM600155", "OMIM613810", "OMIM613428", "OMIM613617", "OMIM600105", "OMIM312600", "OMIM613801", "OMIM600156", "OMIM612712", "OMIM613861", "OMIM606068", "OMIM616394", "OMIM615565", "OMIM617433", "OMIM612572", "OMIM600132", "OMIM615725", "OMIM616188", "OMIM613767", "OMIM614494", "OMIM400004", "OMIM601414", "OMIM618613", "OMIM617781", "OMIM615922", "OMIM613983", "OMIM300605", "OMIM607921", "OMIM613794", "OMIM180105", "OMIM614180", "OMIM612165", "OMIM615233", "OMIM613756", "OMIM608133", "OMIM602594", "OMIM312612", "OMIM601718", "OMIM613711", "OMIM613862", "OMIM300029", "OMIM616544", "OMIM618826", "OMIM618345", "OMIM606875", "OMIM613750", "OMIM613731", "OMIM613660", "OMIM613758", "OMIM608462", "OMIM613582", "OMIM617023", "OMIM609913" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:37.977829" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "388" }, { "type": "Disease", "id": "791" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI038/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI038/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "81" }, { "type": "SmallVariant", "id": "82" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI038/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI038/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "741" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI038/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI038/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI038/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI038/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "32" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI038/?format=api" } }, { "type": "Combination", "id": "OLI039", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 2, "final_metascore": 3 }, "omim_id": [ "OMIM615994", "OMIM615996", "OMIM615992", "OMIM615988", "OMIM615983", "OMIM615991", "OMIM209900", "OMIM617406", "OMIM615981", "OMIM605231", "OMIM617119", "OMIM615990", "OMIM600151", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM615985", "OMIM615986", "OMIM615987", "OMIM615982", "OMIM615989" ], "oligogenic_effect": "True Digenic", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:37.993754" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "81" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "741" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "32" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/?format=api" } }, { "type": "Combination", "id": "OLI062", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM615994", "OMIM615996", "OMIM615992", "OMIM615988", "OMIM615983", "OMIM615991", "OMIM209900", "OMIM617406", "OMIM615981", "OMIM605231", "OMIM617119", "OMIM615990", "OMIM600151", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM615985", "OMIM615986", "OMIM615987", "OMIM615982", "OMIM615989" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:38.387839" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "123" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "44" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/?format=api" } }, { "type": "Combination", "id": "OLI063", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615994", "OMIM615996", "OMIM615992", "OMIM615988", "OMIM615983", "OMIM615991", "OMIM209900", "OMIM617406", "OMIM615981", "OMIM605231", "OMIM617119", "OMIM615990", "OMIM600151", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM615985", "OMIM615986", "OMIM615987", "OMIM615982", "OMIM615989" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:38.407046" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "124" }, { "type": "SmallVariant", "id": "125" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "45" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/?format=api" } }, { "type": "Combination", "id": "OLI064", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615994", "OMIM615996", "OMIM615992", "OMIM615988", "OMIM615983", "OMIM615991", "OMIM209900", "OMIM617406", "OMIM615981", "OMIM605231", "OMIM617119", "OMIM615990", "OMIM600151", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM615985", "OMIM615986", "OMIM615987", "OMIM615982", "OMIM615989" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:38.427090" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "126" }, { "type": "SmallVariant", "id": "127" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "46" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/?format=api" } }, { "type": "Combination", "id": "OLI065", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM615994", "OMIM615996", "OMIM615992", "OMIM615988", "OMIM615983", "OMIM615991", "OMIM209900", "OMIM617406", "OMIM615981", "OMIM605231", "OMIM617119", "OMIM615990", "OMIM600151", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM615985", "OMIM615986", "OMIM615987", "OMIM615982", "OMIM615989" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:38.442620" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "128" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "46" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/?format=api" } }, { "type": "Combination", "id": "OLI066", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615994", "OMIM615996", "OMIM615992", "OMIM615988", "OMIM615983", "OMIM615991", "OMIM209900", "OMIM617406", "OMIM615981", "OMIM605231", "OMIM617119", 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