Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/variants/3061/combinations/?format=api&ordering=combination_id
{ "data": [ { "type": "Combination", "id": "OLI1458", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Tunisian", "lastmodified": "2023-05-16T12:02:58.326789" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1458/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1458/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3060" }, { "type": "CopyNumberVariant", "id": "3061" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1458/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1458/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "960" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1458/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1458/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1458/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1458/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "553" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1458/?format=api" } }, { "type": "Combination", "id": "OLI1621", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:24.771001" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1621/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1621/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "CopyNumberVariant", "id": "3061" }, { "type": "SmallVariant", "id": "3418" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1621/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1621/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "974" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1621/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1621/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1621/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1621/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "552" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1621/?format=api" } }, { "type": "Combination", "id": "OLI1622", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:24.833936" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1622/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1622/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "CopyNumberVariant", "id": "3061" }, { "type": "SmallVariant", "id": "3419" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1622/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1622/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "974" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1622/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1622/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1622/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1622/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1147" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1622/?format=api" } }, { "type": "Combination", "id": "OLI1623", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:24.897277" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1623/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1623/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "CopyNumberVariant", "id": "3061" }, { "type": "SmallVariant", "id": "3420" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1623/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1623/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "974" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1623/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1623/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1623/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1623/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "176" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1623/?format=api" } }, { "type": "Combination", "id": "OLI1624", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:24.960617" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1624/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1624/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "CopyNumberVariant", "id": "3061" }, { "type": "SmallVariant", "id": "3421" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1624/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1624/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "974" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1624/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1624/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1624/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1624/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1147" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1624/?format=api" } }, { "type": "Combination", "id": "OLI1625", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:25.022548" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1625/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1625/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "CopyNumberVariant", "id": "3061" }, { "type": "SmallVariant", "id": "3422" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1625/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1625/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "974" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1625/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1625/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1625/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1625/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1148" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1625/?format=api" } }, { "type": "Combination", "id": "OLI1626", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM606070", "OMIM617892", "OMIM606640", "OMIM613954", "OMIM614696", "OMIM616208", "OMIM613435", "OMIM105400", "OMIM615515", "OMIM614808", "OMIM615426", "OMIM608030", "OMIM300857", "OMIM608627", "OMIM612069", "OMIM617839", "OMIM612577", "OMIM205250", "OMIM611895", "OMIM616437", "OMIM608031" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:25.085660" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1626/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1626/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "CopyNumberVariant", "id": "3061" }, { "type": "SmallVariant", "id": "3423" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1626/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1626/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "974" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1626/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1626/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1626/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1626/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1149" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1626/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 7 } }