Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/55/combinations/?format=api&ordering=-oligogenic_effect
{ "data": [ { "type": "Combination", "id": "OLI069", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.511850" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI069/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI069/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "136" }, { "type": "SmallVariant", "id": "137" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI069/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI069/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "693" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI069/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI069/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI069/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI069/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "49" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI069/?format=api" } }, { "type": "Combination", "id": "OLI070", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.527605" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI070/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI070/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "138" }, { "type": "SmallVariant", "id": "139" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI070/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI070/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "693" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI070/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI070/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI070/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI070/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "49" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI070/?format=api" } }, { "type": "Combination", "id": "OLI071", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.543056" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI071/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI071/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "139" }, { "type": "SmallVariant", "id": "140" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI071/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI071/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "693" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI071/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI071/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI071/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI071/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "50" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI071/?format=api" } }, { "type": "Combination", "id": "OLI072", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.557987" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI072/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI072/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "141" }, { "type": "SmallVariant", "id": "142" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI072/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI072/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "693" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI072/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI072/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI072/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI072/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "49" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI072/?format=api" } }, { "type": "Combination", "id": "OLI073", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:38.572256" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI073/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI073/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "143" }, { "type": "SmallVariant", "id": "144" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI073/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI073/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "693" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI073/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI073/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI073/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI073/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "51" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI073/?format=api" } }, { "type": "Combination", "id": "OLI1095", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Pakistani", "lastmodified": "2022-08-04T14:15:33.863265" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1095/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1095/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2384" }, { "type": "SmallVariant", "id": "2385" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1095/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1095/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "909" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1095/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1095/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1095/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1095/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "51" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1095/?format=api" } }, { "type": "Combination", "id": "OLI1096", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Pakistani", "lastmodified": "2022-08-04T14:15:33.938312" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1096/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1096/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2384" }, { "type": "SmallVariant", "id": "2385" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1096/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1096/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "909" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1096/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1096/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1096/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1096/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "51" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1096/?format=api" } }, { "type": "Combination", "id": "OLI1097", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Pakistani", "lastmodified": "2022-08-04T14:15:34.013299" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1097/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1097/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2384" }, { "type": "SmallVariant", "id": "2385" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1097/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1097/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "909" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1097/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1097/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1097/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1097/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "51" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1097/?format=api" } }, { "type": "Combination", "id": "OLI1098", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Pakistani", "lastmodified": "2022-08-04T14:15:34.138329" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1098/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1098/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2386" }, { "type": "SmallVariant", "id": "2387" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1098/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1098/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "909" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1098/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1098/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1098/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1098/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "51" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1098/?format=api" } }, { "type": "Combination", "id": "OLI1099", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Pakistani", "lastmodified": "2022-08-04T14:15:34.213344" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "55" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1099/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1099/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "138" }, { "type": "SmallVariant", "id": "2387" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1099/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1099/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "909" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1099/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1099/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1099/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1099/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "51" } } }, 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"relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 10 } }