Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/3153/combinations/?format=api&ordering=-ethnicity
{ "data": [ { "type": "Combination", "id": "OLI290", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 2 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.271039" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI290/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI290/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "560" }, { "type": "SmallVariant", "id": "561" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI290/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI290/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI290/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI290/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI290/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI290/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "192" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI290/?format=api" } }, { "type": "Combination", "id": "OLI291", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.287093" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI291/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI291/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "562" }, { "type": "SmallVariant", "id": "563" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI291/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI291/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI291/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI291/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI291/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI291/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "193" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI291/?format=api" } }, { "type": "Combination", "id": "OLI292", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 3 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.303214" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI292/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI292/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "564" }, { "type": "SmallVariant", "id": "565" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI292/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI292/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI292/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI292/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI292/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI292/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "194" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI292/?format=api" } }, { "type": "Combination", "id": "OLI293", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.319119" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI293/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI293/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "566" }, { "type": "SmallVariant", "id": "567" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI293/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI293/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI293/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI293/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI293/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI293/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "195" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI293/?format=api" } }, { "type": "Combination", "id": "OLI294", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 3 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.334937" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI294/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI294/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "568" }, { "type": "SmallVariant", "id": "569" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI294/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI294/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI294/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI294/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI294/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI294/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "194" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI294/?format=api" } }, { "type": "Combination", "id": "OLI295", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 3 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.350600" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI295/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI295/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "570" }, { "type": "SmallVariant", "id": "571" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI295/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI295/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI295/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI295/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI295/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI295/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "196" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI295/?format=api" } }, { "type": "Combination", "id": "OLI296", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.372614" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI296/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI296/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "572" }, { "type": "SmallVariant", "id": "573" }, { "type": "SmallVariant", "id": "574" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI296/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI296/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI296/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI296/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI296/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI296/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "197" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI296/?format=api" } }, { "type": "Combination", "id": "OLI297", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.386970" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI297/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI297/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "575" }, { "type": "SmallVariant", "id": "576" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI297/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI297/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI297/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI297/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI297/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI297/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "198" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI297/?format=api" } }, { "type": "Combination", "id": "OLI298", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 3, "final_metascore": 3 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:42.402170" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "3153" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI298/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI298/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "577" }, { "type": "SmallVariant", "id": "578" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI298/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI298/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI298/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI298/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI298/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI298/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "199" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI298/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 9 } }