Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/2227/combinations/?format=api&ordering=-oligogenic_effect
{ "data": [ { "type": "Combination", "id": "OLI1245", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European", "lastmodified": "2023-05-16T12:02:42.214594" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1245/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1245/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2634" }, { "type": "SmallVariant", "id": "2635" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1245/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1245/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "932" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1245/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1245/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1245/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1245/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "878" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1245/?format=api" } }, { "type": "Combination", "id": "OLI1243", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European", "lastmodified": "2023-05-16T12:02:42.082241" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1243/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1243/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1219" }, { "type": "SmallVariant", "id": "2632" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1243/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1243/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "932" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1243/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1243/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1243/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1243/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "876" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1243/?format=api" } }, { "type": "Combination", "id": "OLI1244", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European", "lastmodified": "2023-05-16T12:02:42.141960" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1244/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1244/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1219" }, { "type": "SmallVariant", "id": "2633" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1244/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1244/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "932" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1244/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1244/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1244/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1244/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "877" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1244/?format=api" } }, { "type": "Combination", "id": "OLI161", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:40.113620" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI161/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI161/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "323" }, { "type": "SmallVariant", "id": "325" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI161/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI161/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "641" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI161/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI161/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI161/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI161/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "115" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI161/?format=api" } }, { "type": "Combination", "id": "OLI162", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:40.129262" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI162/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI162/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "326" }, { "type": "SmallVariant", "id": "327" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI162/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI162/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "641" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI162/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI162/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI162/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI162/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "115" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI162/?format=api" } }, { "type": "Combination", "id": "OLI163", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:40.144847" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI163/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI163/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "327" }, { "type": "SmallVariant", "id": "328" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI163/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI163/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "641" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI163/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI163/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI163/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI163/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "115" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI163/?format=api" } }, { "type": "Combination", "id": "OLI164", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:40.160503" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI164/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI164/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "323" }, { "type": "SmallVariant", "id": "329" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI164/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI164/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "641" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI164/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI164/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI164/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI164/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "115" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI164/?format=api" } }, { "type": "Combination", "id": "OLI576", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Turkish", "lastmodified": "2021-11-16T17:59:47.903806" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI576/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI576/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1219" }, { "type": "SmallVariant", "id": "1220" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI576/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI576/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "795" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI576/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI576/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI576/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI576/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "388" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI576/?format=api" } }, { "type": "Combination", "id": "OLI577", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Turkish", "lastmodified": "2021-11-16T17:59:47.925656" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI577/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI577/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1221" }, { "type": "SmallVariant", "id": "1222" }, { "type": "SmallVariant", "id": "1223" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI577/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI577/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "795" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI577/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI577/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI577/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI577/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "389" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI577/?format=api" } }, { "type": "Combination", "id": "OLI936", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2022-08-04T14:15:09.984449" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI936/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI936/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2026" }, { "type": "SmallVariant", "id": "2027" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI936/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI936/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "876" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI936/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI936/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI936/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI936/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "698" } } }, 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